Climate change, locust plagues in Africa, emerging novel viruses such as Covid-19, widespread environmental degradation, planetary boundaries (e.g., Rockström et al. 2009; Steffen et al. 2015): there are all symptoms of the true underlying problem — our flawed relationship with the natural environment. But we only have to turn to the natural environment to see the solutions. Even as we recognize human well-being and our social and economic systems depend entirely on natural systems, we continue to experience unprecedented environmental challenges largely as a consequence of unsustainable interactions with nature. “Sustainability” has entered our lexicon, but the word itself does not specify sustainability of what and for whom over what time period? In this talk, I argue that sustainability has little meaning in and of itself and that regenerative solutions that follow design principles emerging from natural systems are by definition indefinitely sustainable. I use the design principles that we followed in planting our permaculture orchard to highlight these issues. Extractive capitalism and large-scale, commodity-based, resource- and energy-intensive farming are not regenerative and consequently lead to adverse outcomes. Nature’s design principles provide a blueprint for regenerative economic and social systems embedded within the biosphere.